Pacific Northwest National Laboratory Jobs

Job Information

Pacific Northwest National Laboratory Cryo-EM Microscopist & Biochemist in RICHLAND, Washington

Organization and Job ID

Job ID: 310684

Directorate: Earth & Biological Sciences

Division: Environmental Molecular Sciences

Group: Functional & Systems Biology

Job Description

This position is responsible for providing cryo-EM user support for the Environmental Molecular Sciences Laboratory (EMSL) at the Pacific Northwest National Laboratory (PNNL).

Activities include:

  • Assisting in the day-to-day running of a new Krios G3i, general lab maintenance, providing end user training, and large cryo-EM data set acquisition for single particle, micro-ED and tomography projects.

  • The incumbent will be expected to help maintain a smooth and efficient working environment. This includes troubleshooting sample preparations and setting up long semi-automated data collection runs for user projects.

  • Demonstrated substantial experience utilizing transmission electron microscopes and developing cryo sample preparation, imaging and analysis methodologies

  • Strong working knowledge of instrumentation and techniques used in structural biology and biochemistry laboratories

  • Demonstrated ability to learn new and innovative procedures quickly

  • Maintain a high level of professional expertise through familiarity with current scientific literature

  • Ability to multi-task efficiently and demonstrate good time management skills

  • Excellent communication skills with strong ability to organize, document and analyze research data

  • Demonstrated ability to work independently and as a team member to accomplish research goals

  • Demonstrated knowledge of basic computer software for data generation and record keeping

  • Experience managing a laboratory supply inventory, reagent preparation, and waste disposal

  • Experience handling chemical and biologically hazardous materials

  • Ability to follow lab safety regulations and lab compliance protocols

Minimum Qualifications

BS/BA with 2 years of experience. MS/MA with 0 years of experience. PhD with 0 years of experience

Preferred Qualifications

  • PhD or MS/MA with relevant experience with cryo-EM and biochemistry or structural biology preferred.

  • Demonstrated experience as a lead/key contributor for projects and/or tasks.

  • Demonstrated experience initiating projects, planning, and working independently to complete projects.

  • Demonstrated strong organizational skills.

  • Computer skills, including word processing, web searching, database entry, spreadsheet and/or database creation.

  • Able to work under pressure of deadlines, frequent interruptions, and changing priorities.

  • Research experience in structural biology from data acquisition to atomic modeling

  • 1+ years experience in cryo-EM (single particle, micro-ED, tomography)

  • Previous experience using FEI Titan Krios with energy filter, phase plate and direct electron detectors.

Equal Employment Opportunity

Battelle Memorial Institute (BMI) at Pacific Northwest National Laboratory (PNNL) is an Affirmative Action/Equal Opportunity Employer and supports diversity in the workplace. All employment decisions are made without regard to race, color, religion, sex, national origin, age, disability, veteran status, marital or family status, sexual orientation, gender identity, or genetic information. All BMI staff must be able to demonstrate the legal right to work in the United States. BMI is an E-Verify employer. Learn more at

Please be aware that the Department of Energy (DOE) prohibits DOE employees and contractors from participation in certain foreign government talent recruitment programs. If you are offered a position at PNNL and are currently a participant in a foreign government talent recruitment program you will be required to disclose this information before your first day of employment.

Directorate: Earth & Biological Sciences

Job Category: Scientists/Scientific Support

Group: Functional and Systems Biology

Opening Date: 2020-03-18

Closing Date: 2020-04-01